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Exiling a card using its plot ability is a special action. Once you announce you're taking that action, no other player can respond by trying to remove that card from your hand.

If a plotted card has {X} in its mana cost, you must choose 0 as the value of X when casting it without paying its mana cost.

If the plotted card's owner casts it, the spell has no relation to the spell that player originally cast. Any choices made for the original spell or effects affecting the original spell aren't carried over to the new one.

If you're casting a plotted card from exile without paying its mana cost, you can't choose to cast it for any other alternative costs. You can, however, pay additional costs, such as kicker costs. If the plotted card has any mandatory additional costs, those must still be paid to cast the spell.

Plot abilities are written "Plot [cost]," which means "Any time you have priority during your main phase while the stack is empty, you may pay [cost] and exile this card from your hand. It becomes plotted."

Spells that can't be countered can still be exiled by Aven Interrupter's triggered ability. They won't resolve.

You can't cast a plotted card on the same turn it became plotted. On any future turn, you may cast that card from exile without paying its mana cost during your main phase while the stack is empty.

If an instant or a card with flash is plotted this way, you can still cast it only when you have priority during your main phase while the stack is empty.